Inflammatory Bowel Disease, or IBD, refers to a group of intestinal diseases that occur due to prolonged inflammation in the digestive system. Inflammation in the digestive tract can disrupt normal digestive functions and result in disturbing symptoms such as diarrhea, constipation and indigestion. The immunological causes of Inflammatory Bowel Disease tend to worsen the symptoms of these diseases.
Ulcerative Colitis and Crohn’s disease are common inflammatory bowel disorders. IBD can be painful and disrupt the routine life of patients. In some cases, IBD may lead to serious complications resulting in life-threatening consequences.
Hence, it is important to identify the causes of Inflammatory Bowel Disease and correct the factors responsible. This article is focused on providing information on the role of the immune system in the development of Inflammatory Bowel Disease.
What are the Immunological Causes of Inflammatory Bowel Disease?
Inflammation is the basic mechanism responsible for triggering the causes of Inflammatory Bowel Disease. The immune system plays a role in contributing to inflammatory changes in the intestines, thus worsening the symptoms of IBD.
Research studies have indicated that the release of pro-inflammatory substances, such as cytokines, by the immune system can trigger the pathogenesis of IBD, including Crohn’s disease and Ulcerative Colitis.
It is also found that abnormal functions of the immune system can create imbalances in the anti-inflammatory and pro-inflammatory cytokines. These abnormalities contribute to the causes of inflammatory bowel disease as it prevents the resolution of inflammation and results in tissue destruction and disease perpetuation.
Hence, correcting immune system function is recommended to control the symptoms of inflammatory bowel disease.
Abnormalities of the adaptive immunity have been found to be responsible for triggering the causes of inflammatory bowel disease. Research studies have revealed that T cells, which regulate the immune responses especially inflammation, tend to proliferate in patients with IBD.
The functions of the subtypes of T helper cells, which eliminate the pathogenic agents and control allergic reactions, are also hampered in patients with IBD. These findings indicate the role of the immune system in triggering the causes of inflammatory bowel disease.
The Innate Immune System
The innate immune system controls digestive functions, including intestinal mucosal epithelial barrier and innate immune molecules. The innate immune system is involved in adaptive immunity, and also presents antigens for the original T cells in order to provide activation signals.
The innate immune system is also involved in the maturity and differentiation of the immune cells regulating inflammation and immune functions.
However, research studies have indicated that these protective mechanisms of the immune system are hampered in patients suffering from IBD. Research studies have proven that an improperly functioning innate immune system can worsen the causes of inflammatory bowel disease as it fails to control inflammation.
This can result in considerable damage to the mucosal lining of the intestine resulting in corrosion and ulcerations. Hence, taking steps to correct the functions of the innate immune system is recommended to control inflammation in the intestine and prevent IBD.
The role of the immune system in the causes of Inflammatory Bowel Disease has been proven during several research studies. IBD is a chronic, progressive ailment marked by periods of remissions and exacerbations. The recurring symptoms of this disease can have an adverse impact on the person’s routine life. Hence, sufferers are advised to seek immunological intervention to control IBD in a safe and effective manner.
BioPro-Plus is a natural immunity-boosting supplement that can help people to control the immunological causes of Inflammatory Bowel Disease. This supplement can help to regulate the functions of the adaptive and innate immune systems. This could prevent inflammatory changes in the intestine and inhibit damage to the mucosa.
These benefits of BioPro-Plus can help to prevent corrosion and ulceration in the intestine thereby relieving the symptoms of IBD. Regular use of this supplement can also help to reduce the frequency and intensity of the exacerbations of IBD and improve the quality of person’s life.