Probiotics are living microorganisms, such as strains of healthy bacteria, that provide numerous health benefits. Regular use of supplements containing probiotics for controlling inflammation have been highly recommended for reducing the risk of diseases that occur due to inflammation, oxidative stress, infections, and immunological dysfunctions. 

 Unlike bacteria and other microorganisms that cause infections, the strains of healthy bacteria are actually helpful for protecting the body against serious conditions. These healthy bacteria reside in the gut forming gut flora, also called the gut microbiota. 

Here is a brief discussion about the benefits of probiotics for controlling inflammation and how these supplements could provide protection against inflammatory, infective, and immunological disorders. 

Benefits of Probiotics for Controlling Inflammation

Immunomodulatory Effects 

The regular use of probiotics for controlling inflammation is linked to a reduced risk of immunological disorders. Research studies have revealed that the digestive tract hosts millions of microorganisms, which form the gut microbiota. In the case of an opportunistic invasion, the abundant population of bacteria in the intestinal tissues could lead to potential health issues such as infections and inflammation. The functions of the immune system have evolved to sustain the symbiotic relationship between the host and the microbiota in these cases. 

On the other hand, to sustain this homeostasis, the gut microbiota also exerts an immunoregulatory effect. This microbial community modifies the host’s physiological, immunological, and metabolic functions and drives the immune system’s maturation during the early years of life, thus contributing to the maintenance of homeostasis throughout life. 

The use of probiotics for controlling inflammation could improve the diversity of gut flora thereby increasing mucus secretion and preventing the destruction of junction proteins by lowering the number of LPSs (lipopolysaccharides). When these LPSs bind the endothelial cells to the toll-like receptors, macrophage and dendritic cells are activated. 

Furthermore, using probiotics may minimize the secretion of inflammatory biomarkers and prevent the unnecessary stimulation of the immune system thereby preventing inflammation. 

These findings point to the benefits of using probiotics for controlling inflammation and supporting immunological functions. 

Effect on Intestinal Chronic Diseases

Using probiotics for controlling inflammation can help reduce the risk of intestinal chronic diseases. Probiotics play a role in the modulation of the immune system thereby regulating the body’s anti-inflammatory response. 

Research studies have revealed that probiotic strains could reduce the expression of pro-inflammatory cytokines by producing an action mediated by the toll-like receptors.

Probiotics may also improve the clinical symptoms and histological alterations in patients with intestinal chronic diseases such as IBD (inflammatory bowel diseases) including Crohn’s disease and ulcerative colitis. 

These findings point to the benefits of using probiotic supplements on a regular basis in order to protect the gut against chronic inflammatory diseases.  

It is also possible to derive these benefits by including probiotic foods in the diet such as yogurt, kefir, and kombucha. 

Probiotics Isolated from Infant Feces

Natural strains of probiotics isolated from infant feces have been shown to produce anti-inflammatory effects that could protect the child against the risk of inflammatory and immunological disorders. These probiotics can stimulate the mechanisms linked to anti-oxidation, cholesterol reduction, inhibition of α-glucosidase activity, and anti-inflammation. 

Probiotics may also inhibit the release of inflammatory mediators like tumor necrosis factors and interleukins substantially. 

Additionally, studies related to whole genome sequencing and the comparative genomic analysis of strains like 4M13 and 4B15 have indicated them to be novel genomic strains. These findings suggest that 4M13 and 4B15 isolated from infant feces possess the highest probiotic potential. These strains could produce a favorable impact on the immune system by regulating the release of pro-inflammatory cytokines and protect the child against a number of disorders linked to inflammation. 

The results of this study clearly point to the benefits of probiotics for controlling inflammation and regulating immune system functions. 

Immunity-boosting supplements like BioPro-Plus can also be highly beneficial for helping to reduce the risk of diseases linked to inflammation. Just like probiotics, BioPro-Plus also has the potential to support the activities of immune cells, reduce inflammation, prevent oxidative stress, and lower the risk of infections. 

Patients suffering from inflammatory or immunological disorders can consider using BioPro-Plus and probiotics for controlling inflammation and reducing their risk of complications. Regular use of probiotics with BioPro-Plus could help patients derive the benefits of both these supplements and allow them to stay healthy and reduce the risk of developing serious consequences. 

References:

  • https://www.frontiersin.org/articles/10.3389/fimmu.2021.578386/full
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490534/
  • https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0192021